Assessment of the methodological, recommendation and reporting quality of global guidelines for neck pain and synthesis of evidence and recommendations: a systematic review protocol

Author:

Li Jiayu,Ou Jiayin,Liu Yang,Shen Chenwei,Chen Xiaoli,Li Ying,Zhao Jiayi,Xu JingORCID,Zhang YuORCID,Wang LinORCID

Abstract

IntroductionNeck pain is a global health problem that can cause severe disability and a huge medical burden. Clinical practice guideline (CPG) is an important basis for clinical diagnosis and treatment. A high-quality CPG plays a significant role in clinical practice. However, the quality of the CPGs for neck pain lacks comprehensive assessment. This protocol aims to evaluate the methodological, recommendation, reporting quality of global CPGs for neck pain and identify key recommendations and gaps that limit evidence-based practice.MethodCPGs from January 2013 to November 2023 will be identified through a systematic search on 13 scientific databases (PubMed, Cochrane Library, Embase, etc) and 7 online guideline repositories. Six reviewers will independently evaluate the quality of CPGs for neck pain by using the Appraisal of Guidelines for Research and Evaluation, the Appraisal of Guidelines Research and Evaluation-Recommendations Excellence and the Reporting Items for Practice Guidelines in Healthcare tools. Intraclass correlation coefficient will be used to test the consistency of the assessment. We will identify the distribution of evidence and recommendations in each evidence-based CPGs for neck pain and regrade the level of evidence and strength of recommendations by adopting the commonly used Grading of Recommendations, Assessment, Development and Evaluations system. The key recommendations based on high-quality evidence will be summarised. In addition, we will categorise CPGs by different characteristics and conduct a subgroup analysis of the results of assessment.Ethics and disseminationNo subjects will be involved in this systematic review, so there is no need for ethical approval. The finding of this review will be summarised as a paper for publication in a peer-reviewed journal.PROSPERO registration numberCRD42023417717.

Funder

the College Students' Innovative Entrepreneurial Training Plan Program

the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine

the Special project of "Lingnan modernization of traditional Chinese medicine" in 2019 Guangdong Provincial R & D Program

Key laboratory Program of universities in guangdong province

the Youth Program of the National Natural Science Foundation of China

the Zhaoyang Talent Special Project from Guangdong Provincial Hospital of Chinese Medicine

Publisher

BMJ

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