Swiss Frailty Network and Repository: protocol of a Swiss Personalized Health Network’s driver project observational study

Author:

Gagesch MichaelORCID,Edler Karin,Chocano-Bedoya Patricia O,Abderhalden Lauren A,Seematter-Bagnoud Laurence,Meyer Tobias,Bertschi Dominic,Zekry Dina,Büla Christophe JORCID,Gold Gabriel,Kressig Reto W,Stuck Andreas E,Bischoff-Ferrari Heike AORCID

Abstract

IntroductionEarly identification of frailty by clinical instruments or accumulation of deficit indexes can contribute to improve healthcare for older adults, including the prevention of negative outcomes in acute care. However, conflicting evidence exists on how to best capture frailty in this setting. Simultaneously, the increasing utilisation of electronic health records (EHRs) opens up new possibilities for research and patient care, including frailty.Methods and analysisThe Swiss Frailty Network and Repository (SFNR) primarily aims to develop an electronic Frailty Index (eFI) from routinely available EHR data in order to investigate its predictive value against length of stay and in-hospital mortality as two important clinical outcomes in a study sample of 1000–1500 hospital patients aged 65 years and older. In addition, we will examine the correlation between the eFI and a test-based clinical Frailty Instrument to compare both concepts in Swiss older adults in acute care settings. As a Swiss Personalized Health Network (SPHN) driver project, our study will report on the characteristics and usability of the first nationwide eFI in Switzerland connecting all five Swiss University Hospitals’ Geriatric Departments with a representative sample of patients aged 65 years and older admitted to acute care.Ethics and disseminationThe study protocol was approved by the competent ethics committee of the Canton of Zurich (BASEC-ID 2019-00445). All acquired data will be handled according to SPHN’s ethical framework for responsible data processing in personalised health research. Analyses will be performed within the secure BioMedIT environment, a national infrastructure to enable secure biomedical data processing, an integral part of SPHN.Trial registration numberNCT04516642.

Funder

Swiss Personalized Health Network

participating University Hospitals in-kind contributions of the same amount

Publisher

BMJ

Subject

General Medicine

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