Protein kinase C inhibits cyclic adenosine monophosphate generation by histamine and truncated glucagon like peptide 1 in the human gastric cancer cell line HGT-1.

Author:

McKenna P,Williams J M,Gespach C P,Hanson P J

Publisher

BMJ

Subject

Gastroenterology

Reference27 articles.

1. All of kinase C produces a specific inhibition of the these receptors are coupled to adenylate cyclase effects of histamine and TGLP-1 on adenylate in HGT-1 cells."-'4 To enable the identification cyclase activity in a human gastric cancer cell of the sites of action of protein kinase C, the line by acting at a site close to their receptors. actions of TPA on the cyclic AMP response to,1993

2. The molecular heterogeneity of protein kinase C and its implications for cellular regulation;Nishizuka, Y.;Nature,1988

3. Intracellular signalling and gastric acid secretion;Hanson, P.J.; Hatt, J.F.;QuartJ Exptl Physiol,1989

4. -(1-36) amide: potent cAMP-dependent stimuli of rat parietal cell function;Schmidtler, J.; Schepp, W.; Janczewska, I.; Weigert, N.; Furlinger, C.; Schusdziarra, V.; Classen, M.;GLP-1-(7-36),1991

5. Involvement of calcium-sensitive phospholipid-dependent protein kinase in control of acid secretion by isolated rat parietal cells;Anderson, N.G.; Hanson, P.J.;BiochemJI,1985

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