AND INHALED ANESTHETICS ON THE INDICATORS OF THE GAS COMPOSITION OF THE BLOOD OF PIGS

Abstract

The physiological characteristics of the pig organism determine the difficulties of general anesthesia. In this regard, the actual problem in providing adequate anesthesia in this type of animal is the prevention and control of respiratory and circulatory disorders. The aim of the work was to assess the adequacy of anesthesia in pigs according to the gas composition and acid-base state (CBS) of blood, which underwent surgical manipulations under general anesthesia during experimental studies. The object of the study was 16 pigs (6 boars, 10 sows) aged from four to six months. The work is devoted to comparing the dynamics of blood gas composition indicators at various stages of intravenous anesthesia with zoletil and inhalation anesthesia with isoflurane in order to prevent and timely detect hypoxemia and hypercapnia in pigs. The division of hypoxemia and hypercapnia by severity based on clinical symptoms, laboratory studies of the gas composition of arterial blood made it possible to objectively assess the condition of the animal and provide it with the necessary assistance in a timely manner. The study of the acid-base state of the blood showed that with both types of anesthesia, the greatest changes during induction and during awakening are affected by the amount of carbon dioxide tension in arterial blood (РaСO2). During the induction period, it increased both with the introduction of the zoletil and with the use of isoflurane, respectively, by 26.6% and 14.1% compared with the initial values. During the awakening period, the value of PaCO2 decreased by 10.7% compared to the previous value with anesthesia with zoletil and by 7.2% with inhalation of isoflurane.