Author:
Uppicherla Suchitra,Tadimarri Divya Sree,K. N. Nandha Kumar,Rajaboyna Haritha,Yadavendra Reddy K. D.,Ponnolu Gowtham Kumar Reddy,Cuddapah Rajaram,B. Jeevan Kumar
Abstract
ABSTRACT;
Introduction: Statins are highly preferred drugs in the treatment and prevention of atherosclerotic diseases. Statins usage increased in the last two decades. DUE is a cyclic quality-enhancing procedure in the prescription of drugs. Methods: Our study engaged in compiling various prescribing conditions for statins, assessing their effectiveness and safety, and comparing the lipid profile images of atorvastatin and rosuvastatin. A prospective observational study with the involvement of 150 volunteers The complete data collected is analysed using SAS and Microsoft Excel software. Statistical methods of mean, standard deviation, clinical significance, and Z value are calculated.
Results: Atorvastatin (20 mg, 40 mg, and 80 mg) and Rosuvastatin (5 mg and 10mg) are widely used in the primary, secondary, and tertiary prevention of atherosclerotic cardiovascular and cerebrovascular problems. Average reduction of LDL and total cholesterol levels to 106.5(SD ±11.04) and 203.53 (SD±94) respectively.
Key words: Atorvastatin, cardiovascular and cerebrovascular problems, non
adherence, Re-occurrence, Rosuvastatin.
Publisher
Global Pharmacovigilance Society