Author:
Xiao Tixian,Chen Jianan,Liu Qian
Abstract
AbstractIn rectal cancer treatment, the diagnosis and management of lateral pelvic lymph nodes (LLN) are critical for preventing local recurrence. Over time, scholars have reached a consensus: when imaging suggests LLN metastasis, combining neoadjuvant chemoradiotherapy (nCRT) with selective LLN dissection (LLND) can mitigate the risk of recurrence. Selective LLND typically encompasses lymph nodes in the internal iliac and obturator regions. Recent studies emphasize distinctions between internal iliac and obturator lymph nodes regarding prognosis and treatment outcomes, prompting the need for differentiated diagnostic and treatment approaches.
Funder
Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences
National Key Research and Development Program of China
Publisher
Springer Science and Business Media LLC
Reference62 articles.
1. Group MS, et al. Relevance of magnetic resonance imaging-detected pelvic sidewall lymph node involvement in rectal cancer. Br J Surg. 2011;98(12):1798–804.
2. Kroon HM, et al. Systematic review and meta-analysis of long-term oncological outcomes of lateral lymph node dissection for metastatic nodes after neoadjuvant chemoradiotherapy in rectal cancer. Eur J Surg Oncol. 2022;48(7):1475–82.
3. Pampiglione T, Konishi T, Chand M. Invited Commentary. Selective lateral pelvic lymph node dissection in low rectal cancer-planning for future directions. Surgery. 2024;175(2):564–5.
4. Zhou S, et al. Feasibility, indications, and Prognostic significance of selective lateral pelvic lymph node dissection after preoperative chemoradiotherapy in Middle/Low rectal Cancer: results of a Multicenter lateral node study in China. Dis Colon Rectum. 2024;67(2):228–39.
5. Laparoscopic Surgery Committee of the Endoscopist Branch in the Chinese Medical Doctor, A., et al., [Chinese expert consensus on the diagnosis and treatment for lateral lymph node metastasis of rectal cancer ( et al. 2024 edition)]. Zhonghua Wei Chang Wai Ke Za Zhi, 2024. 27(1): pp. 1–14.