Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression

Author:

Sorrentino Zachary A.,Goodwin Marshall S.,Riffe Cara J.,Dhillon Jess-Karan S.,Xia Yuxing,Gorion Kimberly-Marie,Vijayaraghavan Niran,McFarland Karen N.,Golbe Lawrence I.,Yachnis Anthony T.,Giasson Benoit I.ORCID

Funder

National Institute of Neurological Disorders and Stroke

National Institute on Aging

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Pathology and Forensic Medicine

Reference114 articles.

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2. Anderson JP, Walker DE, Goldstein JM, de Laat R, Banducci K, Caccavello RJ, Barbour R, Huang J, Kling K, Lee M, Diep L, Keim PS, Shen X, Chataway T, Schlossmacher MG, Seubert P, Schenk D, Sinha S, Gai WP, Chilcote TJ (2006) Phosphorylation of Ser-129 is the dominant pathological modification of α-Synuclein in familial and sporadic Lewy body disease. J Biol Chem 281:29739–29752. https://doi.org/10.1074/jbc.M600933200

3. Arai Y, Yamazaki M, Mori O, Muramatsu H, Asano G, Katayama Y (2001) Alpha-synuclein-positive structures in cases with sporadic Alzheimer’s disease: morphology and its relationship to tau aggregation. Brain Res 888:287–296. https://doi.org/10.1016/s0006-8993(00)03082-1

4. Baba M, Nakajo S, Tu PH, Tomita T, Nakaya K, Lee VM, Trojanowski JQ, Iwatsubo T (1998) Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson’s disease and dementia with Lewy bodies. Am J Pathol 152:879–884

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