Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau-Reference-Cited by-同舟云学术

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Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau

Published:2017-07-31 Issue:1 Volume:5 Page:
ISSN:2051-5960
Container-title:Acta Neuropathologica Communications
language:en
Short-container-title:acta neuropathol commun

Author:

Strang Kevin H.,Goodwin Marshall S.,Riffe Cara,Moore Brenda D.,Chakrabarty Paramita,Levites Yona,Golde Todd E.,Giasson Benoit I.

Funder

National Institute of Neurological Disorders and Stroke

National Institute on Aging

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1186/s40478-017-0458-0.pdf

Reference49 articles.

1. Andreadis A, Brown WM, Kosik KS (1992) Structure and novel exons of the human tau gene. Biochemistry 31:10626–10633

2. Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT (1992) Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42:631–639

3. Asuni AA, Boutajangout A, Quartermain D, Sigurdsson EM (2007) Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements. J Neurosci 27:9115–9129. doi: 10.1523/JNEUROSCI.2361-07.2007

4. Bi M, Ittner A, Ke YD, Gotz J, Ittner LM (2011) Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice. PLoS One 6:e26860. doi: 10.1371/journal.pone.0026860

5. Boimel M, Grigoriadis N, Lourbopoulos A, Haber E, Abramsky O, Rosenmann H (2010) Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice. Exp Neurol 224:472–485. doi: 10.1016/j.expneurol.2010.05.010

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