Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects, 1-year follow-up: a cluster-randomised trial

Author:

Nsangi Allen,Semakula Daniel,Oxman Andrew D.ORCID,Austvoll-Dahlgren Astrid,Oxman Matt,Rosenbaum Sarah,Morelli Angela,Glenton Claire,Lewin Simon,Kaseje Margaret,Chalmers Iain,Fretheim Atle,Ding Yunpeng,Sewankambo Nelson K.

Abstract

Abstract Introduction We evaluated an intervention designed to teach 10- to 12-year-old primary school children to assess claims about the effects of treatments (any action intended to maintain or improve health). We report outcomes measured 1 year after the intervention. Methods In this cluster-randomised trial, we included primary schools in the central region of Uganda that taught year 5 children (aged 10 to 12 years). We randomly allocated a representative sample of eligible schools to either an intervention or control group. Intervention schools received the Informed Health Choices primary school resources (textbooks, exercise books and a teachers’ guide). The primary outcomes, measured at the end of the school term and again after 1 year, were the mean score on a test with two multiple-choice questions for each of the 12 concepts and the proportion of children with passing scores. Results We assessed 2960 schools for eligibility; 2029 were eligible, and a random sample of 170 were invited to recruitment meetings. After recruitment meetings, 120 eligible schools consented and were randomly assigned to either the intervention group (n = 60 schools; 76 teachers and 6383 children) or the control group (n = 60 schools; 67 teachers and 4430 children). After 1 year, the mean score in the multiple-choice test for the intervention schools was 68.7% compared with 53.0% for the control schools (adjusted mean difference 16.7%; 95% CI, 13.9 to 19.5; P < 0.00001). In the intervention schools, 3160 (80.1%) of 3943 children who completed the test after 1 year achieved a predetermined passing score (≥ 13 of 24 correct answers) compared with 1464 (51.5%) of 2844 children in the control schools (adjusted difference, 39.5%; 95% CI, 29.9 to 47.5). Conclusion Use of the learning resources led to a large improvement in the ability of children to assess claims, which was sustained for at least 1 year. Trial registration Pan African Clinical Trial Registry (www.pactr.org), PACTR201606001679337. Registered on 13 June 2016.

Funder

Norges Forskningsråd

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Reference35 articles.

1. Chalmers I, Oxman AD, Austvoll-Dahlgren A, Ryan-Vig S, Pannell S, Sewankambo N, et al. Key Concepts for Informed Health Choices: a framework for helping people learn how to assess treatment claims and make informed choices. BMJ Evid Based Med. 2018;23(1):29–33.

2. Austvoll-Dahlgren A, Oxman AD, Chalmers I, Nsangi A, Glenton C, Lewin S, et al. Key concepts that people need to understand to assess claims about treatment effects. J Evid Based Med. 2015;8:112–25.

3. Nsangi A, Semakula D, Oxman DA, Sewankambo KN. Teaching children in low income countries to assess claims about treatment effects: a prioritisation of key concepts. J Evid Based Med. 2015;8(4):173–80.

4. Informed Health Choices Group. Teachers’ guide for the Health Choices Book: learning to think carefully about treatments. A health science book for primary school children. Oslo: Norwegian Institute of Public Health; 2016. https://www.informedhealthchoices.org/wp-content/uploads/2016/08/IHC-V3-Teachers-guide_with-cover_Nov2016_lowres.pdf. Accessed 11 Feb 2019.

5. Nsangi A, Semakula D, Rosenbaum S, Oxman AD, Oxman M, Morelli A, et al. Development of the Informed Health Choices resources in four countries to teach primary school children to assess claims about treatment effects. 2019. In press. https://www.informedhealthchoices.org/wp-content/uploads/2016/08/IHC-primary-school-resources-development_IHC-Working-paper-2017.pdf

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