First human dose-escalation study with remogliflozin etabonate, a selective inhibitor of the sodium-glucose transporter 2 (SGLT2), in healthy subjects and in subjects with type 2 diabetes mellitus-Reference-Cited by-同舟云学术

First human dose-escalation study with remogliflozin etabonate, a selective inhibitor of the sodium-glucose transporter 2 (SGLT2), in healthy subjects and in subjects with type 2 diabetes mellitus

Published:2013-05-13 Issue:1 Volume:14 Page:
ISSN:2050-6511
Container-title:BMC Pharmacology and Toxicology
language:en
Short-container-title:BMC Pharmacol Toxicol

Author:

Kapur Anita,O’Connor-Semmes Robin,Hussey Elizabeth K,Dobbins Robert L,Tao Wenli,Hompesch Marcus,Smith Glenn A,Polli Joseph W,James Jr Charles D,Mikoshiba Imao,Nunez Derek J

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Link

http://link.springer.com/article/10.1186/2050-6511-14-26/fulltext.html

Reference26 articles.

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3. Giugliano D, Standl E, Vilsboll T, Betteridge J, Bonadonna R, Campbell I, Schernthaner G, Staels B, Trichopoulou A, Farinaro E: Is the current therapeutic armamentarium in diabetes enough to control the epidemic and its consequences? What are the current shortcomings?. Acta Diabetol. 2009, 46: 173-181.

4. Kanai Y, Lee WS, You G, Brown D, Hediger MA: The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. J Clin Invest. 1994, 93: 397-404.

5. Wells RG, Pajor AM, Kanai Y, Turk E, Wright EM, Hediger MA: Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter. Am J Physiol. 1992, 263: F459-F465.

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