Nourishing the clot: a comprehensive review of dietary habits and their implications for platelet function

Abstract

AbstractThis review elucidates the intricate relationship between dietary habits and platelet function, emphasizing the influential role of berries. Both macronutrients and micronutrients in our diet have been found to profoundly affect platelet reactivity and aggregation, presenting a potential therapeutic intervention for platelet-associated disorders. The article particularly highlights the bioactive compounds in berries, such as flavonoids, which have demonstrated a correlation with diminished platelet aggregation and reduced thrombotic risk. The underlying molecular mechanisms, including the modulation of platelet activation pathways, are elaborated upon. Furthermore, the potential clinical implications are explored, suggesting dietary modifications and berry supplementation as complementary approaches to manage platelet-associated conditions. In culmination, the importance of dietary habits, predominantly the consumption of berries, in modulating platelet functionality is underscored, proposing avenues for future investigations in nutritional genomics to devise personalized dietary guidelines.