Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report

Author:

Zhu Changjun,Lv Minjie,Huang Jianling,Zhang Changwen,Xie Lixu,Gao Tianming,Han Bo,Wang Wenjing,Feng GanzhuORCID

Abstract

Abstract Background Chlamydia abortus is generally considered to cause abortion, stillbirth, and gestational sepsis in pregnant women, but it’s rare in bloodstream infection and pneumonia. Case presentation We present details of a patient with bloodstream infection and pneumonia caused by Chlamydia abortus. Both blood next-generation sequencing (NGS) and sputum NGS indicate Chlamydia abortus infection. The patient received intravenous infusion of piperacillin sodium and tazobactam sodium (4.5 g/8 h) and moxifloxacin (0.4 g/d) and oral oseltamivir (75 mg/day). Within one month of follow-up, the patient's clinical symptoms were significantly improved, and all laboratory parameters showed no marked abnormality. However, chest computer tomography (CT) showed the inflammation wasn’t completely absorbed. And we are still following up. Conclusions Chlamydia abortus can cause pneumonia in humans. NGS has the particular advantage of quickly and accurately identifying the infection of such rare pathogens. Pneumonia is generally not life-threatening, and has a good prognosis with appropriate treatment. However, Chlamydia infection can lead to serious visceral complications which clinicians should pay attention to.

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases

Reference23 articles.

1. Bommana S, Polkinghorne A. Mini review: Antimicrobial control of chlamydial infections in animals: current practices and issues. Front Microbiol. 2019;10:113.

2. Longbottom D, Coulter LJ. Animal chlamydioses and zoonotic implications. London: Elsevier; 2003. p. 217–44.

3. Li Z, Cao X, Fu B, Chao Y, Cai J, Zhou J. Identification and Characterization of Chlamydia abortus isolates from Yaks in Qinghai, China. Biomed Res Int. 2015;2015:1–6.

4. Li Z, Liu P, Cao X, Lou Z, Zaręba-Marchewka K, Szymańska-Czerwińska M, Niemczuk K, Hu B, Bai X, Zhou J. First report of Chlamydia abortus in farmed fur animals. Biomed Res Int. 2018;2018:1–6.

5. Campos-Hernández E, Vázquez-Chagoyán JC, Salem AZM, Saltijeral-Oaxaca JA, Escalante-Ochoa C, López-Heydeck SM, de Oca-Jiménez RM. Prevalence and molecular identification of Chlamydia abortus in commercial dairy goat farms in a hot region in Mexico. Trop Anim Health Pro. 2014;46(6):919–24.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3