Author:
Bryant David,Moulton Vincent,Spillner Andreas
Abstract
Abstract
Background
Neighbor-Net is a novel method for phylogenetic analysis that is currently being widely used in areas such as virology, bacteriology, and plant evolution. Given an input distance matrix, Neighbor-Net produces a phylogenetic network, a generalization of an evolutionary or phylogenetic tree which allows the graphical representation of conflicting phylogenetic signals.
Results
In general, any network construction method should not depict more conflict than is found in the data, and, when the data is fitted well by a tree, the method should return a network that is close to this tree. In this paper we provide a formal proof that Neighbor-Net satisfies both of these requirements so that, in particular, Neighbor-Net is statistically consistent on circular distances.
Publisher
Springer Science and Business Media LLC
Subject
Applied Mathematics,Computational Theory and Mathematics,Molecular Biology,Structural Biology
Reference17 articles.
1. Felsenstein J: Inferring phylogenies. 2003, Sinauer Associates
2. Bryant D, Moulton V: NeighborNet: An agglomerative method for the construction of phylogenetic networks. Molecular Biology and Evolution. 2004, 21: 255-265. 10.1093/molbev/msh018.
3. Saitou N, Nei M: The neighbor-joining method: A new method for reconstructing phylogenetic trees. Molecular Biology and Evolution. 1987, 4 (4): 406-425.
4. Hu J, Fu HC, Lin CH, Su HJ, Yeh HH: Reassortment and Concerted Evolution in Banana Bunchy Top Virus Genomes. Journal of Virology. 2007, 81: 1746-1761.
5. Lacher D, Steinsland H, Blank T, Donnenberg M, Whittam T: Sequence Typing and Virulence Gene Allelic Profiling. Journal of Bacteriology. 2007, 189: 342-350.
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