Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response-Reference-Cited by-同舟云学术

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Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response

Published:2015-09-04 Issue:1 Volume:9 Page:
ISSN:1479-7364
Container-title:Human Genomics
language:en
Short-container-title:Hum Genomics

Author:

Azevedo Luisa,Serrano Catarina,Amorim Antonio,Cooper David N.

Funder

FCT-Portuguese Foundation for Science and Technology

Qiagen Inc

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1186/s40246-015-0043-1

Reference69 articles.

1. Klein J. Origin of major histocompatibility complex polymorphism: the trans-species hypothesis. Hum Immunol. 1987;19(3):155–62.

2. Leffler EM, Gao Z, Pfeifer S, Ségurel L, Auton A, Venn O, et al. Multiple instances of ancient balancing selection shared between humans and chimpanzees. Science. 2013;339(6127):1578–82.

3. Cagliani R, Fumagalli M, Riva S, Pozzoli U, Comi GP, Menozzi G, et al. The signature of long-standing balancing selection at the human defensin β-1 promoter. Genome Biol. 2008;9(9):R143-R.

4. Gyllensten UB, Erlich HA. Ancient roots for polymorphism at the HLA-DQ alpha locus in primates. Proc Natl Acad Sci U S A. 1989;86(24):9986–90.

5. Asthana S, Schmidt S, Sunyaev S. A limited role for balancing selection. Trends Genet. 2005;21(1):30–2.

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