Complex host genetics influence the microbiome in inflammatory bowel disease

Author:

Knights Dan,Silverberg Mark S,Weersma Rinse K,Gevers Dirk,Dijkstra Gerard,Huang Hailiang,Tyler Andrea D,van Sommeren Suzanne,Imhann Floris,Stempak Joanne M,Huang Hu,Vangay Pajau,Al-Ghalith Gabriel A,Russell Caitlin,Sauk Jenny,Knight Jo,Daly Mark J,Huttenhower Curtis,Xavier Ramnik J

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine

Reference42 articles.

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2. Abraham C, Cho J: Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflamm Bowel Dis. 2009, 15: 1090-1100. 10.1002/ibd.20894.

3. Knights D, Lassen KG, Xavier RJ: Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome. Gut. 2013, 62: 1505-1510. 10.1136/gutjnl-2012-303954.

4. Morgan XC, Tickle TL, Sokol H, Gevers D, Devaney KL, Ward DV, Reyes JA, Shah SA, LeLeiko N, Snapper SB, Bousvaros A, Korzenik J, Sands BE, Xavier RJ, Huttenhower C: Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment. Genome Biol. 2012, 13: R79-10.1186/gb-2012-13-9-r79.

5. Baumgart M, Dogan B, Rishniw M, Weitzman G, Bosworth B, Yantiss R, Orsi RH, Wiedmann M, McDonough P, Kim SG, Berg D, Schukken Y, Scherl E, Simpson KW: Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn’s disease involving the ileum. ISME J. 2007, 1: 403-418. 10.1038/ismej.2007.52.

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