Author:
Wang Wei,Ju Yuhao,Liu Nan,Shi Shengbo,Hao Lujiang
Abstract
AbstractMany microbial exopolysaccharides (EPS) have been reported in the last decade, and their fermentation processes, functional properties and applications, structural characterization, and biological activities have been extensively studied. Despite the great diversity of biological activities already described for EPS, only a few have been exploited industrially. The main reason for this is that the structure–activity relationship of EPS has not been clearly defined. In this review, we collected EPS-related publications from two databases, the Web of Science and China National Knowledge Infrastructure, and reviewed the correlation between the structural characteristics of EPS and observed biological activity, as reported in studies over the last decade. This review focused on the antioxidant, antitumor, immunomodulatory, hypoglycemic, antibacterial, and gut microbial-modulating activities of EPS. This review aimed to lay a foundation for researching the structure–activity relationship of EPS and provide a theoretical basis for important scientific studies and applications of EPS.
Graphical Abstract
Funder
Natural Science Foundation of Shandong Province
Natural Science Foundation of Shandong Province
Education and Industry Integration Innovation Pilot Project of Qilu University of Technology
State Key Laboratory of Biobased Material and Green Papermaking
Shandong Provincial Key Laboratory of Biosensors
Qilu University of Technology of Cultivating Subject for Biology and Biochemistry, Science, Education and Industry Integration Innovation Pilot Project of Qilu University of Technology
Publisher
Springer Science and Business Media LLC
Subject
Agronomy and Crop Science,Biochemistry,Food Science,Biotechnology