Potential methanol toxicity and the importance of using a standardised alcohol-based hand rub formulation in the era of COVID-19-Reference-Cited by-同舟云学术

Potential methanol toxicity and the importance of using a standardised alcohol-based hand rub formulation in the era of COVID-19

Published:2020-08-08 Issue:1 Volume:9 Page:
ISSN:2047-2994
Container-title:Antimicrobial Resistance & Infection Control
language:en
Short-container-title:Antimicrob Resist Infect Control

Author:

Dear K.,Grayson L.,Nixon R.^ORCID

Abstract

Abstract Objectives Hand sanitisers are urgently needed in the time of COVID-19, and as a result of shortages, some people have resorted to making their own formulations, including the repurposing of distilleries. We wish to highlight the importance of those producing hand sanitisers to avoid methylated spirits containing methanol and to follow WHO recommended formulations. Methods We explore and discuss reports of methanol toxicity through ingestion and transdermal absorption. We discuss the WHO formulations and explain the rationale behind the chosen ingredients. Short conclusion We advise those producing hand sanitisers to follow WHO recommended formulations, and advise those producing hand sanitisers using methylated spirits, to avoid formulations which contain methanol.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health

Link

https://link.springer.com/content/pdf/10.1186/s13756-020-00788-5.pdf

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3. Office of Parliamentary Counsel. Therapeutic Goods (Excluded Goods—Hand Sanitisers) Determination 2020. https://www.legislation.gov.au/Details/F2020L00340. Accessed 30 April 2020.

4. U.S Department of Health and Human Services. Temporary Policy for Preparation of Certain Alcohol-Based Hand Sanitizer Products During the Public Health Emergency ( COVID-19 ) Guidance for Industry. 2020. https://www.fda.gov/media/136289/download. Accessed 30 Apr 2020.

5. World Health Organization. Guide To Local Production: WHO-Recommended Handrub Formulations. 2015. p. 1–9. https://www.who.int/gpsc/5may/Guide_to_Local_Production.pdf.

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