Author:
Sagel Ulrich,Krämer Alexander,Mikolajczyk Rafael T
Abstract
Abstract
Recent studies from Austria, France and Italy have shown that there is a poor adherence to the screening scheme for maternal Toxoplasma infections in pregnancy demonstrated by the fact that many recommended examinations are missed. This leads to undetected infections and limits our knowledge of incidence of the disease. We discuss the negative consequences of this situation on research on treatment effectiveness and the outcomes of congenital toxoplasmosis. The responsible public health institutions should assume responsibility for appropriate surveillance of the screening programme and take measures to improve screening adherence during pregnancy. Screening should start as early as possible in pregnancy and the latest test should be done at delivery. Screening schedule should allow distinguishing infections from the first, second and third trimester of pregnancy, as the risk of materno-foetal transmission and outcomes in case of foetal infections varies by time.
Publisher
Springer Science and Business Media LLC
Reference28 articles.
1. Remington JS, McLeod R, Thulliez P, Desmonts G: Toxoplasmosis. Infectious Diseases of the Fetus and the Newborn Infant. Edited by: Remington JS, Klein JO, Wilson CB, Baker CJ. 2006, Elsevier Saunders, Philadelphia, 947-1091. 6
2. Bénard A, Petersen E, Salamon R, Chêne G, Gilbert R, Salmi LR, et al: The European Toxo Prevention Study Group: Survey of European programmes for the epidemiological surveillance of congenital toxoplasmosis. Eurosurveill. 2008, 13 (15): pii=18834-[cited 2010 Aug 7. http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=18834]
3. Leroy V, Raeber P-A, Petersen E, The European Toxo Prevention Study Group: National public health policies and routines programs to prevent congenital Toxoplasmosis [Unpublished report]. Bordeaux (France). 2005, [cited 2010 Aug 7http://www.eurotoxo.isped.u-bordeaux2.fr]
4. Aspöck H, Pollak A: Prevention of Prenatal Toxoplasmosis by Serological Screening of Pregnant Women in Austria. Scand J Infect Dis. 1992, (Suppl84): 32-38.
5. Petersen E, Remmer Schmidt D: Sulfadiazine and pyrimethamine in the postnatal treatment of congenital toxoplasmosis: what are the options?. Expert Rev Anti-infect Ther. 2003, 1: 175-182. 10.1586/14787210.1.1.175.
Cited by
10 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献