Comparison of topical tofacitinib and 0.1% hypochlorous acid in a murine atopic dermatitis model
Author:
Funder
Realm Therapeutics
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Link
http://link.springer.com/content/pdf/10.1186/s40360-018-0232-3.pdf
Reference15 articles.
1. Akdis CA, Akdis M, Bieber T, Bindslev-Jensen C, Boguniewicz M, Eigenmann P, Hamid Q, Kapp A, Leung DY, Lipozencic J, et al. Diagnosis and treatment of atopic dermatitis in children and adults: European academy of Allergology and clinical immunology/American Academy of allergy, asthma and immunology/PRACTALL consensus report. J Allergy Clin Immunol. 2006;118:152–69.
2. Draelos ZD. Antipruritic hydrogel for the treatment of atopic dermatitis: an open-label pilot study. Cutis. 2012;90:97–102.
3. Fukuyama T, Martel BC, Linder KE, Ehling S, Ganchingco JR, Baumer W. Hypochlorous acid is antipruritic and anti-inflammatory in a mouse model of atopic dermatitis. Clin Exp Allergy. 2018;48:78-88.
4. Bissonnette R, Papp KA, Poulin Y, Gooderham M, Raman M, Mallbris L, Wang C, Purohit V, Mamolo C, Papacharalambous J, Ports WC. Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial. Br J Dermatol. 2016;175:902–11.
5. Fukuyama T, Ehling S, Cook E, Baumer W. Topically administered Janus-kinase inhibitors Tofacitinib and Oclacitinib display impressive antipruritic and anti-inflammatory responses in a model of allergic dermatitis. J Pharmacol Exp Ther. 2015;354:394–405.
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