Author:
Ferry Thomas,Amiet Vivianne,Natterer Julia,Perez Marie-Hélène,Pfister Raymond,Colombier Sébastien,Longchamp David
Abstract
Abstract
Background
Chloroquine use has increased worldwide recently in the setting of experimental treatment for the novel coronavirus disease (Covid-19). Nevertheless, in case of chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its cardiac toxicity.
Case presentation
This case study reports on a 14-years-old girl who presented in cardiac arrest after an uncommon suicide attempt by ingesting 3 g of chloroquine. After 66 min of cardio-pulmonary resuscitation (CPR), extracorporeal cardiopulmonary resuscitation (ECPR) was initiated, allowing cardiac function to recover.
Conclusions
Chloroquine intoxication is a rare but serious condition due to its cardiac toxicity. Use of ECPR in this case of transient toxicity allowed a favorable evolution with little neurological impairment.
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine,Emergency Medicine
Reference15 articles.
1. Phipps C, Chan K, Teo F, et al. Fatal chloroquine poisoning: a rare cause of sudden cardiac arrest. Ann Acad Med Singapore. 2011;40(6):296–7.
2. Marquardt K, Albertson TE. Treatment of hydroxychloroquine overdose. Am J Emerg Med. 2001;19(5):420–4.
3. Messant I, Jeremie N, Lenfant F, et al. Massive chloroquine intoxication: importance of early treatment and pre-hospital treatment. Resuscitation. 2004;60(3):343–6.
4. Ten Broeke R, Mestrom E, Woo L, et al. Early treatment with intravenous lipid emulsion in a potentially lethal hydroxychloroquine intoxication. Neth J Med. 2016;74(5):210–4.
5. Lee HM, Archer JR, Dargan PI, et al. What are the adverse effects associated with the combined use of intravenous lipid emulsion and extracorporeal membrane oxygenation in the poisoned patient? Clin Toxicol (Phila). 2015;53(3):145–50.
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