SIRT6 prevent chronic cerebral hypoperfusion induced cognitive impairment by remodeling mitochondrial dynamics in a STAT5-PGAM5-Drp1 dependent manner-Reference-Cited by-同舟云学术

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SIRT6 prevent chronic cerebral hypoperfusion induced cognitive impairment by remodeling mitochondrial dynamics in a STAT5-PGAM5-Drp1 dependent manner

Published:2024-08-25 Issue:1 Volume:22 Page:
ISSN:1479-5876
Container-title:Journal of Translational Medicine
language:en
Short-container-title:J Transl Med

Author:

Du Yong,He Jiaqing,Xu Yanni,Wu Xun,Cheng Hongbo,Yu Jiegang,Wang Xiaoliang,An Yaqing,Wu Yang,Guo Wei^ORCID

Funder

the National Natural Science Foundation of China

the Natural Science Foundation of Hebei Province

the Scientific Research Fund Project of the Hebei Provincial Health and Family Planning Commission

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1186/s12967-024-05566-0.pdf

Reference41 articles.

1. O’Brien JT, Thomas A. Vascular dementia. Lancet (London England). 2015;386(10004):1698–706.

2. Rajeev V, Fann DY, Dinh QN, Kim HA, De Silva TM, Lai MKP, Chen CL, Drummond GR, Sobey CG, Arumugam TV. Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment. Theranostics. 2022;12(4):1639–58.

3. Poh L, Sim WL, Jo DG, Dinh QN, Drummond GR, Sobey CG, Chen CL, Lai MKP, Fann DY, Arumugam TV. The role of inflammasomes in vascular cognitive impairment. Mol Neurodegeneration. 2022;17(1):4.

4. Inoue Y, Shue F, Bu G, Kanekiyo T. Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease. Mol Neurodegeneration. 2023;18(1):46.

5. Zhao Y, Zhang J, Zheng Y, Zhang Y, Zhang XJ, Wang H, Du Y, Guan J, Wang X, Fu J. NAD(+) improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway. J Neuroinflamm. 2021;18(1):207.

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