Abstract
AbstractBackgroundIntracranial lipomas are rare, congenital lesions, most often located at the midline. Most hypothalamic lipomas are asymptomatic, but some cases have been associated with precocious puberty, hypothermia, headache and/or obesity.Case presentationA 7-year-old boy was referred for short stature and proved to be partially growth-hormone deficient. Magnetic resonance imaging (MRI) revealed a lipoma in the paramedian hypothalamus. Growth hormone treatment resulted in swift and uncomplicated catch-up growth.ConclusionsThe present case appears to be the first to link hypothalamic lipoma to GH deficiency. The neuro-endocrine pathophysiology underpinning this link remains to be explored.
Funder
Onderzoeksraad, KU Leuven
Publisher
Springer Science and Business Media LLC
Reference15 articles.
1. Loddenkemper T, Morris HH, Diehl B, Lachhwani DK. Intracranial lipomas and epilepsy. J Neurol. 2006;253(5):590–3.
2. Jabot G, Stoquart-Elsankari S, Saliou G, Toussaint P, Deramond H, Lehmann P. Intracranial lipomas: clinical appearances on neuroimaging and clinical significance. J Neurol. 2009;256(6):851–5.
3. Yildiz H, Hakyemez B, Koroglu M, Yesildag A, Baykal B. Intracranial lipomas: importance of localization. Neuroradiology. 2006;48(1):1–7.
4. Truwit CL, Barkovich AJ. Pathogenesis of intracranial lipoma: an MR study in 42 patients. Am J Neuroradiol. 1990;11(4):665–74.
5. Joigneau Prieto L, Ruiz Y, Pérez R, De León Luis J. Prenatal diagnosis of pericallosal lipoma: systematic review. Eur J Paediatr Neurol. 2019;23(6):764–82.
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献