Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Link
http://link.springer.com/content/pdf/10.1186/1471-2210-10-3.pdf
Reference39 articles.
1. Mazzocchi F: Complexity in biology. Exceeding the limits of reductionism and determinism using complexity theory. EMBO Rep. 2008, 9 (1): 10-14. 10.1038/sj.embor.7401147.
2. Nobeli I, Favia AD, Thornton JM: Protein promiscuity and its implications for biotechnology. Nat Biotechnol. 2009, 27 (2): 157-167. 10.1038/nbt1519.
3. Erickson RP: From "magic bullet" to "specially engineered shotgun loads": the new genetics and the need for individualized pharmacotherapy. Bioessays. 1998, 20 (8): 683-685. 10.1002/(SICI)1521-1878(199808)20:8<683::AID-BIES12>3.0.CO;2-V.
4. Roth BL, Sheffler DJ, Kroeze WK: Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov. 2004, 3 (4): 353-359. 10.1038/nrd1346.
5. Keiser MJ, Setola V, Irwin JJ, Laggner C, Abbas AI, Hufeisen SJ, Jensen NH, Kuijer MB, Matos RC, Tran TB: et al, Predicting new molecular targets for known drugs. Nature. 2009, 462 (7270): 175-181. 10.1038/nature08506.
Cited by 32 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Use of gene regulatory network analysis to repurpose drugs to treat bipolar disorder;Journal of Affective Disorders;2024-04
2. Network-based drug repurposing for schizophrenia;Neuropsychopharmacology;2024-02-06
3. Repurposing Drugs via Network Analysis: Opportunities for Psychiatric Disorders;Pharmaceutics;2022-07-14
4. Ligand-Gated Ion Channels as Targets for Treatment and Management of Cancers;Frontiers in Physiology;2022-03-08
5. Time Course of Changes in Peripheral Blood Gene Expression During Medication Treatment for Major Depressive Disorder;Frontiers in Genetics;2019-09-18
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3