Genome-scale analysis to the impact of gene deletion on the metabolism of E. coli: constraint-based simulation approach

Author:

Xu Zixiang,Sun Xiao,Yu Shihai

Publisher

Springer Science and Business Media LLC

Subject

Applied Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Structural Biology

Reference23 articles.

1. Bork P: Is there biological research beyond Systems Biology? A comparative analysis of terms. Mol Syst Biol. 2005, 1: Art. No. 2005.0012.

2. Price ND, Papin JA, Schilling CH, Palsson BO: Genome-scale microbial in silico models: the constraints-based approach. Trends Biotechnol. 2003, 21: 162-169. 10.1016/S0167-7799(03)00030-1.

3. Price ND, Reed JL, Palsson BO: Genome-scale models of microbial cells: evaluating the consequences of constraints. Nature Reviews Microbiology. 2004, 2: 886-897. 10.1038/nrmicro1023.

4. Reed JL, Vo TD, Schilling CH, Palsson BO: An expanded genomescale model of Escherichia coli K-12 (iJR904GSM/GPR). Genome Biology. 2003, 4: R54-10.1186/gb-2003-4-9-r54.

5. Feist AM, Henry CS, Reed JL, Krummenacker M, Joyce AR, Karp PD, Broadbelt LJ, Hatzimanikatis V, Palsson BØ: A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information. Molecular Systems Biology. 2007, 3: Art. No. 121.

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