Author:
Abdelattef Samia Aboelnour Abdeltwab,Ibrahim Suzan Farouk,Abdelhamid Wafaa Raft,Mahmoud Fatten Mohamed
Abstract
Abstract
Background
Breast cancer is considered the most serious lesion among different breast lesions. Mammography is the corner stone for screening for detection of breast cancer. It has been modified to digital mammography (DM) and then to digital breast tomosynthesis (DBT). Tomosynthesis is an emerging technique for diagnosis and screening of breast lesions.
The aim of this study is to interrogate whether the addition of DBT to DM helps in better detection and characterization of different breast lesions.
Methods
This is a prospective study carried on 38 female patients according to our inclusion criteria. All patients were evaluated by using DM alone and thereafter with the addition of DBT to DM. Recall rate was calculated, and the imaging findings of each case were correlated with the final diagnosis and follow-up.
Results
DM identified 32 lesions while DBT with DM identified 37 lesions. On DM alone, 17 lesions were characterized as masses, 5 as focal asymmetry, 2 as architectural distortion, 7 as microcalcification and 1 as macrocalcification. With the addition of DBT, 27 lesions were characterized as masses, 1 as focal asymmetry, 1 as architectural distortion, 7 as microcalcification and 1 as macrocalcification. So, there were better detection and characterization of lesions with the addition of DBT than DM alone. The sensitivity, specificity, AUC, positive and negative predictive values were significantly higher with the addition of DBT to DM (100%, 90.5%, 0.952, 90% and 100%, respectively) than with DM (77.8%, 80.9%, 0.794, 77.8% and 80.9%, respectively) for all breast lesions.
Conclusions
The addition of DBT to DM helps in better detection and characterization of different breast lesions. This leads to early detection of breast cancer, improvement of the performance of radiologists and saving time by reduction of recall rate.
Publisher
Springer Science and Business Media LLC
Subject
Radiology, Nuclear Medicine and imaging
Reference32 articles.
1. Akram M, Iqbal M, Daniyal M, Khan A (2017) Awareness and current knowledge of breast Cancer. Biol Res 50:33
2. Alakhras M, Mello-Thoms C, Rickard M, Bourne R, Brennan P. Efficacy of digital breast tomosynthesis for breast cancer diagnosis. Proc SPIE 9037, Medical Imaging 2014: Image Perception, Observer Performance, and Technology Assessment, 90370V (March 11, 2014).
3. Alsheik N, Dabbous F, Pohlman S et al (2018) Comparison of resource utilization and clinical outcomes following screening with digital breast tomosynthesis versus digital mammography: findings from a learning health system. Acad Radiol 60068:1–9
4. Andersson I, Ikeda D, Zackrisson S, Ruschin M, Svahn T, Timberg P et al (2008) Breast tomosynthesis and digital mammography: a comparison of breast cancer visibility and BIRADS classifcation in a population of cancers with subtle mammographic fndings. Eur Radiol 18:2817–2825
5. Bahrs SD, Otto V, Hattermann V et al (2018) Breast tomosynthesis for the clarification of mammographic BI-RADS 3 lesions can decrease follow-up examinations and enables immediate cancer diagnosis. Acta Radiol 59(10):1176–1183
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献