CAESAR models for developmental toxicity

Author:

Cassano Antonio,Manganaro Alberto,Martin Todd,Young Douglas,Piclin Nadège,Pintore Marco,Bigoni Davide,Benfenati Emilio

Publisher

Springer Science and Business Media LLC

Subject

General Chemistry

Reference49 articles.

1. Quigley D, Simmons F, Whyte H, Robertson J, Freshwater D: Variations in reproductive and developmental toxicant identification. J Chem Health Saf. 2010, 17: 29-53.

2. Van der Jagt K, Munn S, Tørsløv J, De Bruijn J: Alternative approaches can reduce the use of test animals under REACH. Addendum to the report "Assessment of additional testing needs under REACH. Effects of (Q)SARS, risk based testing and voluntaryindustry initiatives". 2004

3. Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. OJ L 396, 30.12.2006. 1-849.

4. CAESAR: Computer Assisted Evaluation of industrial chemical Substances According to Regulations. EC project 022674 (SSPI). [http://www.caesar-project.eu]

5. Arena VC, Sussman NB, Mazumdar S, Yu S, Macina OT: The utility of structure-activity relationship (SAR) models for prediction and covariate selection in developmental toxicity: comparative analysis of logistic regression and decision tree models. SAR QSAR Environ Res. 2004, 15: 1-18.

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