Author:
Su Ying,Liu Aimei,Chen Hongguang,Chen Qingjie,Zhao Bo,Gao Runze,Zhang Kangwei,Peng Tie,Zhang Zhenwang,Ouyang Changhan,Zhu Dan
Abstract
AbstractHuman embryonic stem cells and human induced pluripotent stem cells may be used to create 3D tissues called brain organoids. They duplicate the physiological and pathological characteristics of human brain tissue more faithfully in terms of both structure and function, and they more precisely resemble the morphology and cellular structure of the human embryonic brain. This makes them valuable models for both drug screening and in vitro studies on the development of the human brain and associated disorders. The technical breakthroughs enabled by brain organoids have a significant impact on the research of different brain regions, brain development and sickness, the connections between the brain and other tissues and organs, and brain evolution. This article discusses the development of brain organoids, their use in diabetes research, and their progress.
Funder
Hubei University of Science and Technology “Medical Research Special Fund”
Hubei University of Science and Technology “Doctoral Initiation Fund”
Hubei University of Science and Technology “Horizontal cooperation projects”
Natural Science Foundation of Hubei Province
Publisher
Springer Science and Business Media LLC