A 4-week oral toxicity study of L-alanine in rats with a recovery period of 2 weeks
Author:
Affiliation:
1. Healthcare Products Development Center, KYOWA HAKKO BIO CO., LTD.
2. Gotemba Laboratory, BoZo Research Center Inc.
3. Public Relations Department, KYOWA HAKKO BIO CO., LTD.
Publisher
Japanese Society of Toxicology
Link
https://www.jstage.jst.go.jp/article/fts/1/2/1_63/_pdf
Reference8 articles.
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2. Chow, F.C., Dysart, M.I., Hamar, D.W., Lewis, L.D. and Udall, R.H. (1976): Alanine: a toxicity study. Toxicol. Appl. Pharmacol., 37, 491-497.
3. Gullino, P., Winitz, M., Birnbaum, S.M., Cornfield, J., Otey, M.C. and Greenstein, J.P. (1956): Studies on the metabolism of amino acids and related compounds in vivo. I. Toxicity of essential amino acids, individually and in mixtures, and the protective effect of L-arginine. Arc. Biochem. Biophys., 64, 319-332.
4. Man, E.H. and Bada, J.L. (1987): Dietary D-amino acids. Ann. Rev. Nutr., 7, 209-225.
5. Manabe, J., Matsunuma, T., Takahashi, M., Tatematsu, M. and Nishikawa, A. (2000): Digestive tract. In Toxicologic Histopathology (ITO, N., ed.), pp.160, J. Toxicol. Pathol., Nagoya.
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