Accurate detection of drug-induced delayed ventricular repolarization with a suitable correction formula in Langendorff guinea pig heart
Author:
Affiliation:
1. Safety Assessment Department, Chugai Pharmaceutical Co., Ltd.
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
http://www.jstage.jst.go.jp/article/jts/35/5/35_5_687/_pdf
Reference43 articles.
1. A new look at the statistical model identification
2. Moxifloxacin
3. Bazett, H.C. (1920): An analysis of the time-relations of electrocardiograms. Heart, 7, 353-370.
4. Preclinical In Vitro Cardiac Electrophysiology
5. Chaves, A.A., Keller, W.J., O’Sullivan, S., Williams, M.A., Fitzgerald, L.E., McPherson, H.E., Goykhman, D., Ward, P.D., Hoe, C.M., Mixson, L. and Briscoe, R.J. (2006): Cardiovascular monkey telemetry: Sensitivity to detect QT interval prolongation. J. Pharmacol. Toxicol. Methods, 54, 150-158.
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