No obvious toxicological influences of 50 μL microsampling from rats administered phenacetin as a drug with hematological toxicity-Reference-Cited by-同舟云学术

No obvious toxicological influences of 50 μL microsampling from rats administered phenacetin as a drug with hematological toxicity

Published:2022 Issue:5 Volume:47 Page:193-199
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Ohtsuka Hirohiko¹,Takahashi Kazuaki²,Kitaura Harumi¹,Kandori Hitoshi¹,Danbayashi Kenta¹,Higuchi Tomoaki¹,Jinno Fumihiro¹,Nitta Shin-ichiro³,Mori Kanae³,Iwai Atsushi²,Nakai Keiko²,Saito Kosuke⁴,Saito Yoshiro⁴

Affiliation:

1. Axcelead Drug Discovery Partners Inc.

2. LSIM Safety Institute Corporation

3. LSI Medience Co.

4. National Institute of Health Sciences

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/47/5/47_193/_pdf

Reference7 articles.

1. Boelsterli, U.A., Shie, K.P., Brändle, E. and Zbinden, G. (1983): Toxicological screening models: drug-induced oxidative hemolysis. Toxicol. Lett., 15, 153-158.

2. Diehl, K.H., Hull, R., Morton, D., Pfister, R., Rabemampianina, Y., Smith, D., Vidal, J.M. and van de Vorstenbosch, C.; European Federation of Pharmaceutical Industries Association and European Centre for the Validation of Alternative Methods. (2001): A good practice guide to the administration of substances and removal of blood, including routes and volumes. J. Appl. Toxicol., 21, 15-23.

3. ICH. (1994): ICH S3A: Note for guidance on toxicokinetics: The assessment of systematic exposure in toxicity studies. (https://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Safety/S3A/Step4/S3A_Guideline.pdf)

4. ICH. (2017): ICH S3A Q&A focus on microsampling. (https://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Safety/S3A/S3AIWG_Step4_2017_1116.pdf).

5. Robson, J.M. (1965): Toxic effects of aspirin and phenacetin. Practitioner, 194, 85-89.

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