Dose- and time-dependent changes in blood and adrenal levels of multiple steroids in rats after administration of ketoconazole with or without ACTH
Author:
Affiliation:
1. Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/44/9/44_601/_pdf
Reference20 articles.
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2. Briggs, K., Barber, C., Cases, M., Marc, P. and Steger-Hartmann, T. (2015): Value of shared preclinical safety studies - The eTOX database. Toxicol. Rep., 2, 210-221.
3. Elmore, S.A. (2012): Enhanced histopathology of the immune system: a review and update. Toxicol. Pathol., 40, 148-156.
4. Hanukoglu, I. (1992): Steroidogenic enzymes: structure, function, and role in regulation of steroid hormone biosynthesis. J. Steroid Biochem. Mol. Biol., 43, 779-804.
5. Hamdy, D.A. and Brocks, D.R. (2009): Nonlinear stereoselective pharmacokinetics of ketoconazole in rat after administration of racemate. Chirality, 21, 704-712.
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