Low dose of methylmercury (MeHg) exposure induces caspase mediated-apoptosis in cultured neural progenitor cells
Author:
Affiliation:
1. Department of Anatomy, Showa University School of Medicine
2. Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University
3. Laboratory of Biochemistry, Yokohama College of Pharmacy
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/38/6/38_931/_pdf
Reference22 articles.
1. Burke, K., Cheng, Y., Li, B., Petrov, A., Joshi, P., Berman, R.F., Reuhl, K.R and DiCicco-Bloom, E. (2006): Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E. Neurotoxicology, 27, 970-981.
2. Castoldi, A.F., Barni, S., Turin, I., Gandini, C. and Manzo, L. (2000): Early acute necrosis, delayed apoptosis and cytoskeletal breakdown in cultured cerebellar granule neurons exposed to methylmercury. J. Neurosci. Res., 59, 775-787.
3. Fernandes-Alnemri, T., Litwack, G. and Alnemri, E.S. (1994): CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J. Biol. Chem., 269, 30761-30764.
4. Hsu, Y.T., Wolter, K.G. and Youle, R.J. (1997): Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis. Proc. Nat. Acad. Sci. USA, 94, 3668-3672.
5. Kuo, T.C. and Lin-Shiau, S.Y. (2004): Early acute necrosis and delayed apoptosis induced by methyl mercury in murine peritoneal neutrophils. Basic Clin. Pharmacol. Toxicol., 94, 274-281.
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