Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress-Reference-Cited by-同舟云学术

Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress

Published:2013 Issue:3 Volume:38 Page:403-413
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Morita Reiko¹²,Yafune Atsunori¹²,Shiraki Ayako¹²,Itahashi Megu¹²,Ishii Yuji³,Akane Hirotoshi¹,Nakane Fumiyuki¹,Suzuki Kazuhiko⁴,Shibutani Makoto¹,Mitsumori Kunitoshi¹

Affiliation:

1. Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology

2. Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University

3. Division of Pathology, National Institute of Health Sciences

4. Laboratory of Veterinary Toxicology, Tokyo University of Agriculture and Technology

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/38/3/38_403/_pdf

Reference36 articles.

1. Baird, L. and Dinkova-Kostova, A.T. (2011): The cytoprotective role of the Keap1-Nrf2 pathway. Arch. Toxicol., 85, 241-272.

2. Brocks, D.R. (1999): Anticholinergic drugs used in Parkinson’s disease: an overlooked class of drugs from a pharmacokinetic perspective. J. Pharm. Pharmacol. Sci., 2, 39-46.

3. Chang, T.K. (2009): Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines. AAPS J., 11, 590-601.

4. Cheng, K.C., Cahill, D.S., Kasai, H., Nishimura, S. and Loeb, L.A. (1992): 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G→T and A→C substitutions. J. Biol. Chem., 267, 166-172.

5. Croteau, D.L. and Bohr, V.A. (1997): Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J. Biol. Chem., 272, 25409-25412.

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Illicit drug ketamine induces adverse effects from behavioral alterations and oxidative stress to p53-regulated apoptosis in medaka fish under environmentally relevant exposures;Environmental Pollution;2018-06

2. Early life exposure to a rodent carcinogen propiconazole fungicide induces oxidative stress and hepatocarcinogenesis in medaka fish;Aquatic Toxicology;2016-01

3. Small-molecule modulators of the constitutive androstane receptor;Expert Opinion on Drug Metabolism & Toxicology;2015-05-15

4. Two azole fungicides (carcinogenic triadimefon and non-carcinogenic myclobutanil) exhibit different hepatic cytochrome P450 activities in medaka fish;Journal of Hazardous Materials;2014-07

5. Enhanced liver tumor promotion activity in rats subjected to combined administration of phenobarbital and orphenadrine;The Journal of Toxicological Sciences;2013