The Quantitative Prediction of In Vivo Enzyme-Induction Caused by Drug Exposure from In Vitro Information on Human Hepatocytes

Author:

Kato Motohiro,Chiba Koji,Horikawa Masato,Sugiyama Yuichi

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference50 articles.

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2. In vitro approaches to predicting drug interactions in vivo;von Moltke;Biochem. Pharmacol.,1998

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4. Primary human hepatocytes as a tool for the evaluation of structure-activity relationship in cytochrome P450 induction potential of xenobiotics: evaluation of rifampin, rifapentine and rifabutin;Li;Chem. Biol. Interact.,1997

5. The use of human hepatocyte cultures to study the induction of cytochrome P-450;Kostrubsky;Drug Metab. Dispos.,1999

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