The Regulatory Mechanism of <i>Smilax China</i> L. Saponins against Nonalcoholic Fatty Liver Is Revealed by Metabolomics and Transcriptomics
Author:
Affiliation:
1. Metabolomics Laboratory, Guangxi Medical University
2. The Pharmaceutical Department, Guangxi University of Chinese Medicine First Affiliated Hospital
Publisher
Japan Oil Chemists' Society
Link
https://www.jstage.jst.go.jp/article/jos/73/5/73_ess23167/_pdf
Reference33 articles.
1. 1) Brunt, E.M.; Wong, V.W.; Nobili, V.; Day, C.P.; Sookoian, S. et al. Nonalcoholic fatty liver disease. Nat. Rev. Dis. Primers 1, 15080 (2015). doi.org/10.1038/nrdp. 2015.80
2. 2) Neuschwander-Tetri, B.A. Non-alcoholic fatty liver disease. BMC Med. 15, 45 (2017). doi.org/10.1186/s12916-017-0806-8
3. 3) Svegliati-Baroni, G.; Pierantonelli, I.; Torquato, P.; Marinelli, R.; Ferreri, C. et al. Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease. Free Radic. Biol. Med. 144, 293-309 (2019). doi.org/10.1016/j.freeradbiomed.2019.05.029
4. 4) Liu, C.; Liao, J.Z.; Li, P.Y. Traditional Chinese herbal extracts inducing autophagy as a novel approach in therapy of nonalcoholic fatty liver disease. World J. Gastroenterol. 23, 1964-1973 (2017). doi.org/10.3748/wjg.v23.i11.1964
5. 5) Zhao, X.; Chen, R.; Shi, Y.; Zhang, X.; Tian, C. et al. Antioxidant and anti-inflammatory activities of six flavonoids from Smilax glabra Roxb. Molecules 25, 5295 (2020). doi.org/doi:10.3390/molecules25225295
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