Seroprevalence of SARS-CoV-2 IgG antibodies among rural children aged 6-14 years in a selected block of West Bengal, India-Reference-Cited by-同舟云学术

Seroprevalence of SARS-CoV-2 IgG antibodies among rural children aged 6-14 years in a selected block of West Bengal, India

Published:2024-07-11 Issue: Volume: Page:1-8
ISSN:2519-1586
Container-title:IMC Journal of Medical Science
language:en
Short-container-title:

Author:

Shukla Vineeta¹,Shukla Vivek²,Basu Mausumi³,Mondal Aparajita³,Rashid Mamunur³,Saha Ripan⁴

Affiliation:

1. Department of Community Medicine, Infectious Diseases and Beliaghata General Hospital, Kolkata, India

2. Research and Development, Analytical Developmental Laboratory, Intas Pharmaceuticals Limited (Bio-pharma division), Ahmedabad, India

3. Department of Community Medicine, Institute of Post Graduate Medical Education and Research, Kolkata, India

4. State Public Health Cell, Department of Panchayat and Rural Development, West Bengal, India

Abstract

Background and objectives: Children comprised a significant part of the population during the second and third waves of the COVID-19 pandemic. The objectives of this study were to estimate the seroprevalence of COVID-19 IgG antibody among the children aged 6 to 14 years and to determine, if any, the factors associated with seropositivity. Methods: This cross-sectional study was conducted in a selected block of West Bengal, India over a period of 1 year (April 2022-March 2023) among children. Thirty villages in the block were selected by cluster sampling technique. COVID-19 IgM/IgG Rapid Antibody Test Kit (ICMR approved) was used for the detection of SARS-CoV-2 IgG antibodies. Data were analyzed by appropriate statistical tests. Results: Total 600 children were enrolled in the study.SARS-CoV-2 IgG antibody was positive in 57.2% children. The seropositivity rate (91.8%) was significantly (p<0.001) high among children of age group 12 to 14 years. Seropositivity rate was not significantly different between male and female children (46.4% vs. 53.6%; p>0.05). Conclusion: SARS-COV-2 IgG antibody was positive in a high proportion of children residing in rural areas indicating asymptomatic coronavirus infections among rural population. Socio-demographic factors such as higher age group and father’s education were significantly associated with seropositivity. July 2024; Vol. 18(2):010. DOI:https://doi.org/10.55010/imcjms.18.022 *Correspondence: Vineeta Shukla, Department of Community Medicine, Infectious Diseases and Beliaghata General Hospital, Kolkata, India. Email: vineeta1992@gmail.com

Publisher

Ibrahim Medical College

Reference15 articles.

1. Asrani P, Eapen MS, Hassan MI, Sohal SS. Implications of the second wave of COVID-19 in India. The Lancet Respir Med. 2021; 9: e93–4. DOI:https://doi.org/10.1016/S2213-2600(21)00312-X.

2. Rajapakse N, Dixit D. Human and novel coronavirus infections in children: a review. Paediatr Int Child Health. 2021; 41: 36–55. DOI: 10.1080/20469047.2020.1781356.

3. Acevedo L, Piñeres-Olave BE, Niño-Serna LF, Vega LM, Gomez I, Chacón S,et al. Mortality and clinical characteristics of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 in critically ill patients: an observational multicenter study (MISCO study). BMC Pediatr. 2021; 21: 516.DOI: 10.1186/s12887-021-02974-9.

4. World Health Organization. COVID-19 disease in children and adolescents. Scientific Brief [Internet]. Available at: https://www.who.int/publications/i/item/WHO-2019-nCoV-Sci_Brief-Children_and_adolescents-2021.1 [Accessed on April 12, 2024].

5. Xu W, Li X, Dozier M, He Y, Kirolos A, Lang Z, et al. What is the evidence for transmission of COVID-19 by children in schools? A living systematic review. J Glob Health. 2020; 10: 021104. DOI: 10.7189/jogh.10.021104.