Affiliation:
1. UNIVERSITY OF HEALTH SCIENCES, ŞANLIURFA MEHMET AKİF İNAN HEALTH RESEARCH CENTER
Abstract
Background: To compare the increase in platelet count after the transfusion of apheresis and pooled platelet suspensions among patients in the internal medicine intensive care unit.
Methods Patients who received platelet suspension transfusions and were followed up at the internal medicine intensive care unit at Mehmet Akif Inan Training and Research Hospital were evaluated. The patient's platelet counts were administered apheresis, and pooled platelet suspensions were recorded before and after transfusion. The increase in platelet count was calculated. The two groups were statistically compared.
Results: A total of 4,701 platelet suspension transfusions were performed at our hospital between January 1, 2020, and December 31, 2023. Of these transfusions, 2,990 belonged to pooled platelet suspensions and 1,711 to apheresis platelet suspensions.
Conclusion: Platelet suspension transfusion is frequently used in patients receiving internal medicine intensive care. However, there is an ongoing debate concerning whether apheresis or pooled platelet transfusion is more effective in increasing platelet count. In this study, we found a significantly higher increase in platelet count among patients in the internal medicine intensive care unit after apheresis platelet suspension transfusion than pooled platelet suspension transfusion.
Publisher
Turkish Journal of Internal Medicine
Reference14 articles.
1. Vatansever S, Barısık V, Omer Z, Can H. Usage of platelet suspensions. Smyrna Tıp Dergisi. 2012;3:48-53.
2. Salvadori U, Minelli C, Graziotin B, Gentilini I. Single-donor platelet apheresis: observational comparison of the new Haemonetics Universal Platelet protocol with the previous Concentrated Single Donor Platelet protocol. Blood Transfus. 2014 Apr;12(2):220-5. doi: 10.2450/2013.0119-13.
3. Pietersz RNI. Pooled platelet concentrates: an alternative to single donor apheresis platelets? Transfus Apher Sci. 2009 Oct;41(2):115-9. doi: 10.1016/j.transci.2009.07.003.
4. Fontana S, Kellerb P, Taleghanib MB. Platelet recruitment during multiple donor platelet apheresis differs between cell separators. Transfus Med Hemother. 2011;38(3):195-8. doi: 10.1159/000328634.
5. Mowat Y, Hoad V, Haire B, Masser B, Kaldor J, Heywood A, Thorpe R, McManus H, McGregor S. Prevalence of blood donation eligibility in Australia: A population survey. Transfusion. 2023 Aug;63(8):1519-27. doi: 10.1111/trf.17474.