Unraveling the Enigma of Organismal Death: Insights, Implications, and Unexplored Frontiers

Author:

Noble Peter A.1ORCID,Pozhitkov Alexander2,Singh Kanhaiya3,Woods Erik4,Liu Chunyu5,Levin Michael6,Javan Gulnaz7ORCID,Wan Jun3,Abouhashem Ahmed Safwat8,Mathew-Steiner Shomita S.3,Sen Chandan K.3

Affiliation:

1. 1Department of Microbiology, University of Alabama Birmingham, Birmingham, Alabama, United States

2. 2Division of Research Informatics, Beckman Research Institute, City of Hope, Duarte, California, United States

3. 3Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States

4. 4Ossium Health, Indianapolis, Indiana, United States

5. 5Institute for Human Performance, Upstate Medical University, Syracuse, New York, United States

6. 6Department of Biology, Tufts University, Medford, Massachusetts, United States

7. 7Department of Physical and Forensic Sciences, Alabama State University, Montgomery, Alabama, United States

8. 8Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States

Abstract

Significant knowledge gaps exist regarding the responses of cells, tissues, and organs to organismal death. Examining the survival mechanisms influenced by metabolism and environment, this research has the potential to transform regenerative medicine, redefine legal death, and provide insights into life’s physiological limits, paralleling inquiries in embryogenesis.

Funder

Bill and Ann Templeton Foundation

HHS | National Institutes of Health

National Science Foundation

Publisher

American Physiological Society

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Physiology in Perspective;Physiology;2024-09-01

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