Imbalance and dizziness caused by unilateral vestibular schwannomas correlate with vestibulo-ocular reflex precision and bias-Reference-Cited by-同舟云学术

Imbalance and dizziness caused by unilateral vestibular schwannomas correlate with vestibulo-ocular reflex precision and bias

Published:2022-02-01 Issue:2 Volume:127 Page:596-606
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

King Susan¹,Dahlem Kilian¹,Karmali Faisal¹²^ORCID,Stankovic Konstantina M.²,Welling D. Bradley²^ORCID,Lewis Richard F.¹²³^ORCID

Affiliation:

1. Jenks Vestibular Physiology Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts

2. Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts

3. Department of Neurology, Harvard Medical School, Boston, Massachusetts

Abstract

The severity of symptoms associated with unilateral vestibular schwannomas (VS) is poorly correlated with standard yaw-axis vestibulo-ocular reflex (VOR) metrics that are based on response amplitude. In this study, we show that the balance and perceptual dysfunction experienced by patients with VS scales with VOR metrics that capture information about the central signal-to-noise ratio (balance) and central static tone (dizziness), but are not correlated with the VOR gain, which reflects central signal amplitude.

Funder

HHS | NIH | National Institute on Deafness and Other Communication Disorders

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00725.2020

Reference66 articles.

1. Nerve of Origin, Tumor Size, Hearing Preservation, and Facial Nerve Outcomes in 359 Vestibular Schwannoma Resections at a Tertiary Care Academic Center

2. Relationship of Vertigo and Postural Instability in Patients With Vestibular Schwannoma

3. Associations of Video Head Impulse Test and Caloric Testing among Patients with Vestibular Schwannoma