Specific loss of neural sensitivity to interaural time difference of unmodulated noise stimuli following noise-induced hearing loss

Author:

Haragopal Hariprakash1,Dorkoski Ryan1,Pollard Austin R.1,Whaley Gareth A.1,Wohl Timothy R.1,Stroud Noelle C.1,Day Mitchell L.12

Affiliation:

1. Department of Biological Sciences, Ohio University, Athens, Ohio

2. Quantitative Biology Institute, Ohio University, Athens, Ohio

Abstract

Sensorineural hearing loss compromises perceptual abilities that arise from hearing with two ears, yet its effects on binaural aspects of neural responses are largely unknown. We found that, following severe hearing loss because of acoustic trauma, auditory midbrain neurons specifically lost the ability to encode time differences between the arrival of a broadband noise stimulus to the two ears, whereas the encoding of sound level differences between the two ears remained uncompromised.

Funder

HHS | NIH | National Institute on Deafness and Other Communication Disorders

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

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