Affiliation:
1. Laboratoire de Biologie des Hautes Pressions, Faculte de Medecine Nord, Centre National de la Recherche Scientifique, Unite de Recherche Associee-1330, Marseille, France.
Abstract
Free-moving rats chronically implanted in the striatum with multifiber carbon electrodes selective to dopamine were compressed in a helium-oxygen mixture to 80 bars. Extracellular dopamine level and behavioral symptoms of high-pressure neurological syndrome were simultaneously recorded. Under these conditions, the extracellular level of dopamine monitored by differential pulse voltammetry was found to be pressure dependent, and hyperlocomotor activity, a behavioral symptom of high-pressure neurological syndrome, was found to be linked to these pressure-induced changes in dopamine release.
Publisher
American Physiological Society
Subject
Physiology (medical),Physiology
Cited by
35 articles.
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