Affiliation:
1. School of PharmacyWeifang Medical University, Weifang, Shandong, China
Abstract
Our research elucidated that apelin-13 inhibits renin production through the cAMP/PKA/soluble (pro)renin receptor pathway, presenting a promising therapeutic approach for renovascular hypertension (RVHT) by targeting renin expression mechanisms. These findings underscore the potential of apelin-13 as a novel strategy to address RVHT.
Funder
Weifang Science and Technology Development Plan
MOST | National Natural Science Foundation of China
Publisher
American Physiological Society