Metabolic and cardiovascular adaptations to an 8-wk lifestyle weight loss intervention in younger and older obese men-Reference-Cited by-同舟云学术

Metabolic and cardiovascular adaptations to an 8-wk lifestyle weight loss intervention in younger and older obese men

Published:2021-09-01 Issue:3 Volume:321 Page:E325-E337
ISSN:0193-1849
Container-title:American Journal of Physiology-Endocrinology and Metabolism
language:en
Short-container-title:American Journal of Physiology-Endocrinology and Metabolism

Author:

Vion Julie¹,Sramkova Veronika¹²³,Montastier Emilie¹³⁴,Marquès Marie-Adeline¹³,Caspar-Bauguil Sylvie¹³⁴,Duparc Thibaut¹,Martinez Laurent O.¹,Bourlier Virginie¹,Harant Isabelle¹,Larrouy Dominique¹,Moussaoui Nabila¹,Bonnel Sophie¹,Vindis Cécile¹⁵,Dray Cédric¹,Valet Philippe¹,Saulnier-Blache Jean-Sébastien¹,Schanstra Joost P.¹,Thalamas Claire¹⁵,Viguerie Nathalie¹⁴,Moro Cedric¹³^ORCID,Langin Dominique¹³⁴⁶^ORCID

Affiliation:

1. Institute of Metabolic and Cardiovascular Diseases, I2MC Team MetaDiab, Université de Toulouse, INSERM, Université Toulouse III–Paul Sabatier, UMR 1297, F-CRIN/FORCE Network, Toulouse, France

2. Department of Pathophysiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic

3. Franco-Czech Laboratory for Clinical Research on Obesity, Third Faculty of Medicine, Prague, Czech Republic, Paul Sabatier University, Toulouse, France

4. Departments of Nutrition and Clinical Biochemistry, Toulouse University Hospitals, Toulouse, France

5. Clinical Investigation Center, Université de Toulouse, INSERM, Université Toulouse III–Paul Sabatier, Toulouse University Hospitals, CIC1436, F-CRIN/FORCE Network, Toulouse, France

6. Institut Universitaire de France, IUF, Paris, France

Abstract

Rise in obesity and aging worldwide are major trends of critical importance in public health. This study addresses a current challenge in obesity management. Do older obese adults respond differently to a lifestyle intervention composed of moderate calorie restriction and supervised physical activity than younger ones? The main conclusion of the study is that older and younger obese men similarly benefit from the intervention in terms of cardiometabolic risk.

Funder

Region Occitanie

F-CRIN

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology,Endocrinology, Diabetes and Metabolism

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpendo.00109.2021

Reference50 articles.

1. Weight Management in Older Adults

2. Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies