Inspiratory muscle reflex control after incomplete cervical spinal cord injury

Author:

McNaughton Keith M. D.12ORCID,Witherow Jessica L.2,Dupuche Crystal B.2,Peebles Karen C.2,Elphick Tom G.3,Hudson Anna L.134ORCID,McCaughey Euan J.135ORCID,Boswell-Ruys Claire L.163ORCID,Butler Jane E.3ORCID

Affiliation:

1. Neuroscience Research Australia, Randwick, New South Wales, Australia

2. Department of Health Sciences, Macquarie University, Macquarie Park, New South Wales, Australia

3. School of Medical Sciences, University of New South Wales, Kensington, New South Wales, Australia

4. College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia

5. Queen Elizabeth National Spinal Injuries Unit, Glasgow, United Kingdom

6. Department of Physiotherapy, Prince of Wales Hospital, Randwick, New South Wales, Australia

Abstract

Individuals with incomplete cSCI were tested for the presence of a short latency reflex inhibition of inspiratory muscles, by brief airway occlusion. The reflex was 4.5 times more prevalent in this group compared with those with complete cSCI and is similar to the incidence in able-bodied people. Participants without this reflex all had untreated severe OSA, in contrast to those with an IR, who either had no, mild, or treated OSA. This work reveals novel differences in the reflex control of inspiratory muscles across the cSCI population.

Funder

DHAC | National Health and Medical Research Council

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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