Mirtazapine reduces susceptibility to hypocapnic central sleep apnea in males with sleep-disordered breathing: a pilot study-Reference-Cited by-同舟云学术

Mirtazapine reduces susceptibility to hypocapnic central sleep apnea in males with sleep-disordered breathing: a pilot study

Published:2021-07-01 Issue:1 Volume:131 Page:414-423
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Prowting Joel¹²,Maresh Scott¹²,Vaughan Sarah¹²^ORCID,Kruppe Elizabeth¹²,Alsabri Bander¹²,Badr M. Safwan¹²,Sankari Abdulghani¹²³

Affiliation:

1. Sleep Research Laboratory, John D. Dingell Veterans Affairs Medical Center, Detroit, Michigan

2. Wayne State University School of Medicine, Detroit, Michigan

3. Ascension Providence Hospital, Southfield, Michigan

Abstract

To our knowledge, this research study is novel as it is the first study in humans assessing the effect of mirtazapine on CO2 reserve and chemosensitivity in individuals with severe sleep-disordered breathing. This is also the first study to determine the potential therapeutic effects of mirtazapine on sleep parameters in individuals with a spinal cord injury.

Funder

US Department of Veteran's Affairs Career Development Award

US Department of Veteran's Affairs Career Merit Review

HHS | NIH | National Heart, Lung, and Blood Institute

Detroit Medical Center Foundation

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00838.2020

Reference51 articles.