Differences in heart rate responses to upright posture are associated with variations in the high-frequency power of heart rate variability

Author:

Bouquin Heidi1ORCID,Koskela Jenni K.12ORCID,Tikkakoski Antti13ORCID,Honkonen Milja1,Hiltunen Timo P.45ORCID,Mustonen Jukka T.12ORCID,Pörsti Ilkka H.126ORCID

Affiliation:

1. Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

2. Department of Internal Medicine, Tampere University Hospital, Tampere, Finland

3. Department of Clinical Physiology and Nuclear Medicine, Tampere University Hospital, Tampere, Finland

4. Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland

5. Faculty of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

6. Finnish Cardiovascular Research Center Tampere, Tampere University, Tampere, Finland

Abstract

Subjects with similar supine heart rates are characterized by variable increases in heart rate during upright posture. Individual heart rate increases in response to upright posture are highly reproducible as hemodynamic phenotypes and present underlying differences in the modulation of cardiac parasympathetic tone and systemic vascular resistance. These results indicate that resting heart rate obtained in the supine position alone is not an optimal means of classifying people into groups with differences in cardiovascular function.

Funder

Päivikki and Sakari Sohlberg Foundation

Competitive State Research Financing of the Expert Responsibility Area of Tampere University Hospital

The City of Tampere

SKR | Pirkanmaan Rahasto

Sigrid Juséliuksen Säätiö

Sydäntutkimussäätiö

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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