Sleep efficiency and PTSD symptom severity predict microvascular endothelial function and arterial stiffness in young, trauma-exposed women-Reference-Cited by-同舟云学术

Sleep efficiency and PTSD symptom severity predict microvascular endothelial function and arterial stiffness in young, trauma-exposed women

Published:2023-10-01 Issue:4 Volume:325 Page:H739-H750
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Tahsin Chowdhury Tasnova¹²,Michopoulos Vasiliki³^ORCID,Powers Abigail³,Park Jeanie⁴⁵^ORCID,Ahmed Zynab¹²,Cullen Kathryn⁶^ORCID,Jenkins Nathaniel D. M.⁷⁸^ORCID,Keller-Ross Manda¹²^ORCID,Fonkoue Ida T.¹²^ORCID

Affiliation:

1. Division of Physical Therapy, Department of Rehabilitation Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States

2. Division of Rehabilitation Science, Department of Rehabilitation Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States

3. Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, United States

4. Division of Renal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States

5. Department of Veterans Affairs, Research Service Line, Atlanta Veterans Affairs Healthcare Systems, Decatur, Georgia, United States

6. Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota, United States

7. Department of Health and Human Physiology, University of Iowa, Iowa City, Iowa, United States

8. Abboud Cardiovascular Research Center, University of Iowa, Iowa City, Iowa, United States

Abstract

This is the first study to investigate the individual and combined impacts of objective sleep and PTSD symptoms severity on arterial stiffness and microvascular endothelial function in young premenopausal women. We report that in young trauma-exposed women, although low sleep efficiency is associated with overall vascular function (i.e., microvascular endothelial function and arterial stiffness), the severity of PTSD symptoms is specifically associated with microvascular endothelial function, after accounting for age and body mass index.

Funder

HHS | National Institutes of Health

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00169.2023

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