Antiulcer Effect of (−)-cis-2,3-Dihydro-3-(4-Methylpiperazinyl-methyl)-2-Phenyl-1,5-Benzo Hydrochloride (BTM-1086) in Experimental Animals

Author:

YAMAMOTO Hajimu,NAKAMURA Yoshiki,KUNOH Yasuo,ICHIHARA Kenji,NAGASAKA Mitsuaki,ASAI Hajime

Publisher

Elsevier BV

Subject

Pharmacology

Reference33 articles.

1. (−)-cis-2,3-Dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiazepin4(5H)-one hydrochloride (BTM-1086), and related compounds;Ohno;Chem. Pharm. Bull. (Tokyo),1983

2. Synthesis of a new potent antiulcer and gastric secretory inhibiting agent. (−)-cis-2, 3-dihydro-3-(4-methylpjperazinylmethyl)-2-phonyl-1.5-benzothiazepin-4{5H)-one hydrochloride (BTM-1086), and related compounds;Ohno;J. Phaimacobiodyn.,1984

3. Asai, H., Yamamoto, H., Nagasaka, M., Nakamura Y. and Fukagawa, M.: Pharmacological studies of benzothiazepine derivatives (I). Structure-activity relationships. In The 100th Annual Meeting of the Pharmaceutical Society of Japan. Tokyo. 1980. Abstract, p. 283 (1980)

4. Yamamoto, H., Mlyake, J., Asel, H. and Watanabe, K.: Pharmacological Studies of benzothiazepine derivatives (II). Ami-ulcerogenic action of BTM-1042. In The 100th Annual Mooting of The Pharmaceutical Society of Japan, Tokyo. 1980. Abstract, p. 334 (1980)

5. A simple method for the uniform production of gastric ulceration in the rat;Shay;Gastroenterology,1946

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