Synthesis, characterization and structure of the Bis(methyl-cyclopentadienyl)vanadium(IV) carboxylates-Reference-Cited by-同舟云学术

Synthesis, characterization and structure of the Bis(methyl-cyclopentadienyl)vanadium(IV) carboxylates

Published:2005-03-01 Issue:1 Volume:3 Page:157-168
ISSN:2391-5420
Container-title:Open Chemistry
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Author:

Vinklarek Jaromír¹,Honzíĉek Jan¹,Císařová Ivana²,Pavliŝta Martin³,Holubová Jana¹

Affiliation:

1. 1The Department of General and Inorganic Chemistry, University of Pardubice, nám. Ĉs. legií 565, 532 10, Pardubice, Czech Republic

2. 2Department of Inorganic Chemistry, Charles University, Hlavova 2030, 128 40, Prague 2, Czech Republic

3. 3Research Centre “New Inorganic Compounds and Advanced Materials”, University of Pardubice, nám. Ĉs. legií 565, 532 10, Pardubice, Czech Republic

Abstract

AbstractThe 1,1’-dimethylvanadocene dichloride ((C5H4CH3)2VCl2) reacts in aqueous solution with various carboxylic acids giving two different types of complexes. The 1,1’-dimethylvanadocene complexes of monocarboxylic acids (C5H4CH3)2V(OOCR)2 (R=H,CCl3, CF3, C6H5) contain two monodentate carboxylic ligands, whereas oxalic and malonic acids act as chelate compounds of the formula (C5H4CH3)2V(OOC-A-COO) (A=−, CH2). The structure of the (C5H4CH3)2 V(OOCCF3)2 complex was determined by single crystal X-ray diffraction analysis. The isotropic and anisotropic EPR spectra of all the complexes prepared were recorded. The obtained EPR parameter values were found to be in agreement with proposed structures.

Publisher

Walter de Gruyter GmbH

Subject

Materials Chemistry,General Chemistry

Link

http://link.springer.com/content/pdf/10.2478/BF02476246.pdf

Reference29 articles.

1. P. Köpf-Maier and H. Köpf: “Non-Platinum-Group Metal Antitumor Agents: History, Current Status, and Perspectives”, Chem. Rev., Vol. 87, (1987), pp. 1137–1152.

2. P. Köpf-Maier: “Antitumor activity of titanocene dichloride in xenografted human renal-cell carcinoma”, Anticancer Res., Vol. 19, (1999), pp. 493–504.

3. K. Mross, P. Robben-Bathe, L. Edler, J. Baumgart, W. E. Berdel, H. Fiebig and C. Unger: “Phase I clinical trial of a day −1, −3, −5 every 3 weeks schedule with titanocene dichloride (MKT 5) in patients with advanced cancer: A study of the phase I study group of the Association for Medical Oncology (AIO) of the German Cancer Society”, Onkologie, Vol. 23, (2000), pp. 576–579.

4. N. Kroger, U.R. Kleeberg, K. Mross, L. Edler, G. Sass and D.K. Hossfeld: “Phase II clinical trial of titanocene dichloride in patients with metastatic breast cancer”, Onkologie, Vol. 23, (2000), pp. 60–62.

5. P. Ghosh, S. Ghosh, C. Navara, R.K. Narla, A. Benyumov and F.M. Uckun: “X-ray structure, solution properties, and biological activity profile of vanadocene(IV) acetylacetonate complex, [VCp2(acac)](CF3SO3): A dual-function anti-cancer agent with anti-angiogenic and anti-mitotic properties”, J. Inorg. Biochem., Vol. 84, (2001). pp. 241–253.

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