IL-2, IL-6 and IL-8 levels remain unaltered in the course of immunosuppressive therapy after renal transplantation
Author:
Rysz Jacek1, Kocur Eugeniusz1, Blaszczak Robert1, Bartnicki Piotr1, Stolarek Robert2, Piechota Mariusz3
Affiliation:
1. 12nd Department of Family Medicine, Medical University of Lodz, 90-549, Lodz, Poland 2. 2Department of Experimental and Clinical Physiology, Medical University of Lodz, 92-215, Lodz, Poland 3. 3Department of Anaesthesiology and Intensive Care Unit, University Hospital No. 5 in Lodz, Medical University of Lodz, 90-647, Lodz, Poland
Abstract
AbstractCytokines regulate the immune reactions elicited by renal transplantation (RT). This study was designed to investigate the blood serum levels of IL-2, IL-6, IL-8 in 25 RT patients (10 female and 15 male, mean 5.4±2.7 yrs after RT) three times over a six-month period during standard immunosuppressive therapy with cyclosporine A, azathioprine and prednisolone. The levels of IL-2, IL-6 and IL-8 were tested with ELISA Quantikine Human Interleukin Immunoassay (R&D Systems, detection level 7,0.7 and 10 pg/cm3, respectively). There was no significant alternation of blood serum levels of IL-2, IL-6 and IL-8 in the study patients.
Publisher
Walter de Gruyter GmbH
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